Podcast 85: B vitamins lower homocysteine levels, so why don’t they retard the progression of diabetic nephropathy?

A surprise finding: homocysteine is supposed to be a factor in vascular inflammation, but lowering hyperhomocysteinemia in patients with diabetic nephropathy actually accelerated the decline of  their GFRs. What gives?

We have a conversation with Dr. J. David Spence, whose results were just published in JAMA.

Interview-related link:

• JAMA paper on the effect of B vitamins on diabetic nephropathy

News-related links:

• Clopidogrel suffers possible class-effect interference from PPIs
• BMJ paper on hyperemesis gravidarum across generations
• High-test flu vaccine guidance from ACIP
• Brain games and the lack of data supporting their effectiveness

The post Podcast 85: B vitamins lower homocysteine levels, so why don’t they retard the progression of diabetic nephropathy? first appeared on Clinical Conversations.